In another scientific achievement that adds to the research accomplishments of the College of Pharmacy at Ninevah University, the Dean of the College, Professor Dr. Muyassar Mohammed Ali Al-Qotaji, has co-authored a research paper entitled:
“Enteric-Coated Metformin Tablets: In vitro Release and Metabolic Outcomes in High Fat Diet Fed Rats”
The paper was published in the Journal of Pharmaceutical Innovation, an international peer-reviewed journal published by Springer Nature, in Volume 22 (2027).
The study focused on developing enteric-coated metformin tablets and investigating their drug-release characteristics and metabolic effects through laboratory testing and evaluation in an animal model involving rats fed a high-fat diet.
The findings demonstrated that enteric coatings effectively limited drug release under acidic conditions while allowing rapid release in a medium simulating the intestinal environment. The study also reported promising outcomes, including an enhanced glucagon-like peptide-1 (GLP-1) response and improvements in certain lipid parameters, particularly total cholesterol and low-density lipoprotein (LDL) cholesterol, compared with uncoated metformin.
The significance of this research lies in highlighting the potential of pharmaceutical formulation technologies and targeted drug delivery systems to advance drug development and optimize release characteristics, opening new avenues for further investigation into their therapeutic effectiveness.
This scientific publication reflects the valuable contributions of the academic staff at the College of Pharmacy, Ninevah University, and their continued commitment to advancing scientific research and strengthening the University’s presence in internationally recognized specialized scientific journals.
Research Link:
https://doi.org/10.1007/s12247-026-11132-6